E-liquid is the mixture used in vapor products such as e-cigarettes[97] and generally consists of propylene glycolglycerin, water, nicotine, and flavorings.[20]While the ingredients vary[6][63][97] the liquid typically contains 95% propylene glycol and glycerin.[98] There are many e-liquids manufacturers in the USA and worldwide,[99] and upwards of 8,000 flavors.[36] Industry standards have been created and published by the American E-liquid Manufacturing Standards Association (AEMSA).[100] As of August 8, 2016, the FDA extended its regulatory power to include e-cigarettes, e-liquid, and all related products.[101] Under this ruling, the FDA will evaluate certain issues, including ingredients, product features, nd health risks, as well their appeal to minors and non-users.[102] The FDA rule also bans access to minors.[102] A photo ID is now required to buy e-cigarettes,[103] and their sale in all-ages vending machines is not permitted.[102] As of August 2017, regulatory compliance deadlines relating to premarket review requirements for most e-cigarette and e-liquid products have been extended from November 2017 to 2022.[104][105] Come to learn more on AVE40.